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Recombinant Human Defensin,alpha 1 (DEFA1) Protein

  • Cat.No.: AP50130HU

  • Reactivity: Human

To Purchase AP50130HU

Size:
100μg 500μg
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Product Details

生产种属 Human
来源 Prokaryotic expression
宿主 E. coli
同义词 DEF1; DEFA2; MRS; DEFA1; DEFA1B
浓度 1 mg/mL
形态 Lyophilized or Liquid
纯度 > 90% as determined by SDS-PAGE
序列 P59665
标签 N-terminal His-tag
纯化方式 Affinity purification
分子量 9 kDa
应用 Western blotting,ELISA;SDS-PAGE;Antigen;

产品概述

Defensin, alpha 1 also known as human alpha defensin 1, human neutrophil peptide 1 (HNP-1) or neutrophil defensin 1 is a human protein that is encoded by the DEFA1 gene. Human alpha defensin 1 belongs to the alpha defensin family of antimicrobial peptides. Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. It differs from the defensins, alpha 2 and alpha 3 by only one amino acid.
 

使用方法

Reconstitute in PBS or others.
 

稳定性

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
 

存储

Store it under sterile conditions at -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -80℃.
 

存储缓冲液

Lyophilized from 50mM Tris-HCL,0.5mM EDTA,50mM NaCl,pH 7.4
 

注意事项

This product is for research use only, not for diagnostic or therapeutic use.